Volume 3, Issue 6, November 2015, Page: 110-113
In Situ Quantification and 3D Reconstruction of Thrombus in the Superficial Femoral Artery Disease Using Optical Coherence Tomography
Mehmet Cilingiroglu, Arkansas Heart Hospital, Little Rock, AR, USA/Koc University, School of Medicine, Istanbul, Turkey
Massoud Leesar, University of Alabama at Birmingham, Department of Medicine, Section of Cardiology,Birmingham, AL,USA
Taylor Hoyt, University of Texas Health Sciences Center at San Antonio, Department of Medicine, Section of Cardiology, San Antonio, TX, San Antonio, TX, USA
Austin Mcelroy, University of Texas at Austin, Cockrell School of Biomedical Engineering, Austin, TX, USA
Thomas Milner, University of Texas at Austin, Cockrell School of Biomedical Engineering, Austin, TX, USA
Konstantinos Marmagkiolis, Citizens Memorial Hospital, Bolivar, MO, USA /University of Missouri, Columbia MO, USA
Marc D. Feldman, University of Texas Health Sciences Center at San Antonio, Department of Medicine, Section of Cardiology, San Antonio, TX, San Antonio, TX, USA
Vasili Lendel, Arkansas Heart Hospital, Little Rock, AR, USA/Koc University, School of Medicine, Istanbul, Turkey
Received: Oct. 16, 2015;       Accepted: Oct. 24, 2015;       Published: Nov. 10, 2015
DOI: 10.11648/j.ijmi.20150306.12      View  3067      Downloads  52
Abstract
Background: SFA disease accounts for approximately 40% of the symptomatic peripheral artery disease. Atherosclerosis and thrombosis both contribute in the progression of the peripheral arterial disease. Conventional angiography provides little information about the amount of the thrombus burden. Limited data exists on the use of OCT for the evaluation of PAD. Methods: We performed OCT in three patients with SFA disease who underwent peripheral angiogram from January 2011 – December 2014. Using custom-based imaging software we performed 3D reconstruction and quantification of intraluminal thrombus. Results: We identified thrombus formation in all three patients despite absence of evident thrombosis with invasive angiography. The length of the clot ranged from 12.6 - 47.7 mm and the volume from 11.19 - 43.26 mm3). Conclusion: Atherosclerosis and thrombosis both contribute in the progression of the peripheral arterial disease. OCT can accurately quantify the length and the volume of the clot burden. Larger studies are needed to assess their clinical importance in the prevention and management of PAD.
Keywords
OCT, 3D Reconstruction, PAD
To cite this article
Mehmet Cilingiroglu, Massoud Leesar, Taylor Hoyt, Austin Mcelroy, Thomas Milner, Konstantinos Marmagkiolis, Marc D. Feldman, Vasili Lendel, In Situ Quantification and 3D Reconstruction of Thrombus in the Superficial Femoral Artery Disease Using Optical Coherence Tomography, International Journal of Medical Imaging. Vol. 3, No. 6, 2015, pp. 110-113. doi: 10.11648/j.ijmi.20150306.12
Copyright
Copyright © 2015 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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